Mechanistic basis of lineage restriction
Wu, et al. BioRxiv. 2024 Aug.
此項(xiàng)研究突破性地解決了長(zhǎng)期以往困擾學(xué)界的多細(xì)胞性形成之謎。
Mechanistic basis of lineage restriction
Wu, et al. BioRxiv. 2024 Aug.
此項(xiàng)研究突破性地解決了長(zhǎng)期以往困擾學(xué)界的多細(xì)胞性形成之謎。
Prevalence of errors in lab-made plasmids across the globe
Bai, et al. BioRxiv. 2024 Jun.
此項(xiàng)具有警示意義的研究揭示了近50%由實(shí)驗(yàn)室制備的質(zhì)粒載體存在設(shè)計(jì)缺陷或序列錯(cuò)誤。
VectorBuilder平臺(tái)是云舟生物獨(dú)創(chuàng)的 “一站式” 智能載體設(shè)計(jì)平臺(tái),顛覆性地變革實(shí)驗(yàn)室DIY載體效率低下的傳統(tǒng)方式,將科研人員從實(shí)驗(yàn)室DIY載體的繁復(fù)工作中解放出來(lái),支持其自主在線(xiàn)設(shè)計(jì)和訂購(gòu)個(gè)性化載體。 了解更多
云舟生物作為引領(lǐng)全球基因遞送技術(shù)的創(chuàng)新型企業(yè),致力于系統(tǒng)性攻克基因遞送行業(yè)的關(guān)鍵技術(shù)瓶頸,我們的動(dòng)態(tài)一直備受各界關(guān)注。
NLRP3 inflammasome activation through heart-brain interaction initiates cardiac inflammation and hypertrophy during pressure overload
Preneoplastic stromal cells promote BRCA1-mediated breast tumorigenesis
Schwann cell insulin-like growth factor receptor type-1 mediates metastatic bone cancer pain in mice
Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
Glioblastoma remodelling of human neural circuits decreases survival
DNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
In situ FRET-based localization of the N terminus of myosin binding protein-C in heart muscle cells
PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept
Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy homeostasis
Dedifferentiation maintains melanocyte stem cells in a dynamic niche
Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice
SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases
Chaperone-mediated autophagy promotes PCa survival during ARPI through selective proteome remodeling
The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse
Somatic mutations can induce a noninflflamed tumour microenvironment via their original gene functions, despite deriving neoantigens
A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells
Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
Stromal changes in the aged lung induce an emergence from melanoma dormancy
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Modulation of the HIF2α-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy